Showing posts with label cancer. Show all posts
Showing posts with label cancer. Show all posts

Tuesday, February 07, 2012

The Big C

The papers are full of cricketer Yuvraj Singh and his fight with the Big C. I have also known many folks who have battled the same scourge, and come out successful, because of the amazing specific treatments that are available today, across a range of impressive technologies and pharmaceuticals.

One of the reasons, that we have reached this stage, is because , we have a perfectly detailed map of how things are functioning  inside our bodies . Not only that,  but whenever , there have been new advances in the body maps,  pharmaceutics, or even diagnostic tools,  concerned people have made exhaustive documentation, and made it  freely available.

It was not always so. (You can tell I am reading Emperor of Maladies.....).

 Hippocrates, who postulated stuff around 400 BC, defined the human body to be composed of 4 humors or fluids. Blood, black bile, yellow bile, and phlegm. In balance, they defined good health. Out of balance , you were sick.   Claudius Galen, a Greek doctor (AD 160) who treated Romans, defined various illnesses specifically ; like inflammations were related to blood, pus stuff was  related to phlegm, jaundice was related to yellow bile.  Dr Galen specifically  dedicated "trapped" black bile to define cancer, and depression, a perceptive combination. Till about 1533, cancer treatment was all about gory surgeries, hacking of infected body parts, deaths by infection and so on.  Andreas Vesalius , a medical student ,came to Paris from Brussels to study anatomy in the steps of Galen, was aghast at the absence of a "body" map to guide those doctors performing these surgeries, and set about actually "mapping the human body, muscles, nerves, bones, blood vessels et al. He sourced bodies from graveyards, prisons, and such places, and exhaustively mapped and publish his detailed drawings of normal anatomy. More than 200 years later, Matthew Bailie in London, created a similar atlas of a diseased body. Somewhere between 1846 and 1875 anesthesia came into the picture, along with an ability to control wound infections (sepsis), and this formed a very sturdy base on which all kinds of cancer surgeries were done.

Today , amazing nano technologies and pharmaceutical treatment at the genetic marker level are at the forefront of cancer treatment, and many cancers, hitherto considered uncurable,  are now treatable. At the root of all these advances, is clearly, the landmark mapping work done by people like Vesalius and Bailie. You no longer did approximate cuts and hacks.  They laid down the rules of how you approached the body and the diseased section.

Our society today, is afflicted buy one of the biggest cancers one can think of.

Corruption. 

It was not always so.

About 50 years ago,  corruption, like cancer was  not so common or prevalent; possibly , it existed, but was not recognized. Unlike cancer, it was never a matter of life and death, and so it progressed,  step by shameless step,  eating into minds weakened by lack of idols, lack of morals and lack of scruples, but dazzled by prospects, like cancer, of limitless expansion.  Money and power was an excellent DNA.

There has never been an effort to seriously eradicate this cancer; simply because  system maps created to handle this, always have left a loophole. There has been an effort at piecemeal eradication, like in a specific office or department or ministry or section.  It's like concentrating only or eradicating , say breast cancer, without worrying about its possible spread elsewhere.

There has been no  Hippocrates, no Dr Galen, no  Andreas Vesalius, no Matthew Bailie.  The anesthesia has been all about deadening and  repressing the opinions of a discerning and angry public,  under the guise of appointed committees. , whose reports are summarily dismissed. The sepsis continues unabated in society, infecting all sections.  The cancers in society not only spread in numbers, but they have an uncanny ability to pull towards them, sections of society, at higher and higher levels.

We desperately need to have an overall map for handling this, and a set of surgeons and doctors, who will ruthlessly perform radical surgeries, unconcerned with the presumed importance of a particular organ in society. 

Until then, welcome to a world where, society cancers puffed in their malignant selves, proudly move around, destroying a small brave muscle here, an unwilling-to-lie nerve there.   Watch them, hoodwinking powers of "law" radiation,  and countering the chemotherapy discomfort with some "anticipatory "  arrangements.  

Sometimes,  the proverbial  "shoe" thrown by fate,   hits in the form  of a temporary arrest in a jail.  But this "arrest"  of this cancer, is more in the nature of covering it up, malignancies and all, so as to hopefully fade from the public eye.

We keep hearing of candidates in elections having criminal antecedents. Parties have hundreds of such candidates.

If and when they get elected, can we  ever expect them to make rules for the eradication of the Corruption Cancer ?

Can a surgeon with a diseased hand ever operate on a  cancer  and remove it ?   Can money ever rain from the skies ?  Will Mumbai ever be free of potholes, and flooded monsoon roads ?  Will we ever get over our craze for fairness of skin ?    Will money meant for child welfare ever reach those it is meant for ?   Will we ever learn to provide for storage of grains, that currently rot in the rains, while the centre and states point their carcinomic fingers at each other ?

There are no answers. For the above. One may only hope.

....

But I am glad that real cancer research progresses by leaps and bounds; that we have excellent doctors who practice and  translate that into individual therapy regimens for patients,  and that folks like Yuvraj Singh and many other folks of various ages ,  can now have a good prognosis, and return to their active useful lives again ....



 





 

Friday, December 04, 2009

Turning over a new leaf : Tobacco ?

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I am not obsessed with folks in  Parliament and their performances.

I don't even begrudge them their extremely cushy jobs, where they immediately get a fund of  Rs. two crores (20 million) to spend as they like, supposedly for their constituency.

I am not even jealous  of a salary of Rs 12,000 pm, a daily allowance of Rs 500/ - per day in session, a constituency allowance 10,000 pm, 14,000 p m office expense allowance, 32 free air journeys , unlimited  highest class rail and steamer.ship travel per session (for self and spouse/relative/companion), free virtually unlimited landlines and cell telephone service etc etc

And how can I,  say anything about  their ability to get a life and family pension  with travel benefits ,after enjoying a single 5 year session (if the government doesn't fall earlier, due to defections etc) ?

And these are all the visible benefits.    Its not considered advisable to talk about the others.

But why  am I talking at all ?  Lets just say, that after 21 years of Government service, I went to the library of the Institute that gives me a pension,  thinking that one could borrow books as a retiree,  a facility that exists for the so called upper class retirees. The answer was a firm negative.   Regretfully.   The regret had something to do with the fact, that major part of my work had to do with just about everything related to their library circulation software,  including training lectures,  but the rules were made by someone in New Delhi,  who was convinced that the higher your post , the higher your brain and reading ability post retirement , and vice versa.

But maybe times have changed (On second thoughts , no). I just read about our MP's coming up with what looks like a very simplistic solution  regarding tobacco and cigarette consumption.

No rules about who the smoker has to  be. Upper class. Lower class. Invisible class. Exalted class. Royal class.  

Folks in Delhi  differentiate. Crabs don't.


Members of Parliament in India have just come up with what they think is a unique idea. The Parliamentary Committee on Health and Family Welfare has suggested that tobacco companies be asked to include within every cigarette packet, a coupon for a free cancer check up.

While I thought the earlier initiative, of including ghastly pictures of oral cancers on cigarette packets was OK, this one sounds very simplistic. What about free cancer check up coupons for the Gutka (chewing tobacco) packets ? What about those who get their lungs affected by secondary smoke, blown in rings around them by people who should know better ? Do they get coupons as well ? And once you are diagnosed, God forbid, as positive, what about the rest of the expense ? Of surgery ? Of radiation ? Chemotherapy ?

What about  cancer check up coupons along with sales of alcoholic beverages ?  All those shameless companies, that show ads on TV for "Casettes and CD's"  bearing a whiskey brand name , because TV bans the ads otherwise ?

And why not get truck and car manufacturers along with oil companies to issue coupons for cancer checkups of the respiratory kind ,  since they do much to spoil the air quality around me ?    Maybe three wheeler manufacturers can give an extra coupon . Cars, trucks, three wheelers increasing by huge leaps and bounds in Mumbai, people taking loans to buy them, and the least the sellers can do is give free coupons with each sale. 

By the same logic,  the Mumbai Metropolitan Regional  Development Authority (MMRDA), along with the Municipal Authorities,  can issue coupons for Orthopaedic and Neurological checkups.  A  senior person, travelling across town  for a conference with a group in an official  bus, had a briefcase fall on his head when the bus went through a pothole, and was rushed in for a checkup on arrival at the venue. He was a neighbour earlier, and told me himself.  Another colleague, developed scoliosis after travelling for a year by a bus, to a different venue for  work on a daily basis.  ( Mumbai buses are not about cushioned seats, sanitized air and polite conversation with your neighbor as you traipse daintily to the exit).

And the possibilities of what could happen to the coupons  make me shudder.  Someone will come up with counterfeit coupons.  With unscrupolous folks in business for creating bogus Ration cards, Passports, PAN cards, College marksheets,   this kind of coupon production will be like asking a Ph.D to teach kindergarten.  The market will be flooded with these check up coupons. There may even be made-to-order coupons, for maladies of choice.  Further policing rules by the government will naturally lead to creative flouting of the same.

In the meanwhile, political parties will smile and accept massive political donations from tobacco companies, give candidatures to people close to Gutka manufacturing,   accept gratis flights in planes belonging to alcoholic drinks manufacturers at election time,  and turn a dangerous blind eye to the flouting of rules by road contractors with the right connections up there.

A government that can spend crores on security  for their top people,  specialized stem cell treatments abroad for selected politicians, and millions on decorations for various inaugurations, shouldn't find it difficult to subsidize  and encourage cigarette manufacturers to  enter the new field of  using the tobacco plant as a vaccine factory.   Yes. That's not a misprint or a figment of my imagination.

According to a study coauthored by  Ronald Levy, an oncologist at the Stanford University School of Medicine and reported in Scientific American :

"......anti-cancer vaccines work by pumping a patient full of the same protein / antigen that is on the surface of tumor cells. Researchers believe that if the body contains enough of the protein, the immune system will recognize it as a potential danger and send out armies of disease-killing cells to seek and destroy tumors harboring it.

Researchers took a sample of a patient's tumors, (white blood cells that help the body battle disease and infection). They then extracted the gene from the cells that coded for the antigen they needed (to help the immune system recognize the tumors as threats).

The scientists achieved this by inserting the gene into a plant microbe known a tobacco mosaic virus (TMV). Plants are infected with TMV simply by scratching their leaves and depositing the virus into the tears. Researchers discovered that the virus spreads throughout tobacco plants within a week, in the process cranking out a surfeit of the coveted proteins. The scientists ground the leaves and separated out the antigen, which they then injected into volunteers and noticed encouraging results."


I am aware that tobacco manufacturers are cognizant of this research.  There was recently a presentation in New  Delhi about this.  

In a typical scenario, they (MNC's) will sell off their inventory stock in Third world countries with lax rules, when the First world makes new rules , banning things.  This must stop..

We have the knowledge, we have the trained humanpower for research and the facilities.  We have numerous tobacco plantations, possibly nurtured by these companies.  We, in India need to take the initiative and persuade these companies to turn to vaccine production.

Not coupons. Buy one cigarette pack, get  two free : a coupon, and cancer .

Is it too much to hope that those in power , take an initiative in furthering and implementing the research and look beyond filling party coffers ?

Or is research  all about introducing genetically modified  Monsanto aubergines (baingans)  to the nation ?